Labeled Impurities - ALL Chemistry-Custom Chemical Solutions Supplier

Labeled Impurities

The Introduction of Labeled Impurities:

Impurities in pharmacy refer to substances that have no therapeutic effect, affect the stability and curative effect of drugs, or are even harmful to human health. Impurities have no therapeutic effect and may affect the stability and efficacy of the drug or the scientific management of the drug. Some impurities even have toxic side effects that damage human health. In the research, production, storage, and clinical application of drugs, it is necessary to maintain their purity and reduce their impurities so as to ensure their effectiveness and safety. Impurities in drugs may come from various sources, such as drug production, storage, and sales. The existence of impurities not only affects the quality of drugs but also reflects the problems existing in the processes of production, storage, and transportation. Impurities contained in drugs are the main factors that affect their purity. For example, if the impurities contained in drugs exceed the limit, the physicochemical constants may change, the appearance traits may vary, and the stability of the drugs may be affected. Generally, the structure, appearance, physical and chemical constants, impurity inspection, and content determination of drugs can be regarded as an interrelated whole to evaluate their purity.

In drug development, production, transportation, storage, etc., it is necessary to maintain the purity of the active ingredients of the drug, reduce the impurity content of the drug, and maximize the effectiveness and safety of the drug. Isotope labeling is a trace analysis method that uses radioactive isotopes as tracers to label research objects. Isotope-labeled impurities contain one or more isotopic atoms in their molecules. Except for isotopic effects, the chemical properties of isotope-substituted impurities are generally unchanged. Thus, labeled impurity standards can participate in similar chemical reactions and are traceable. Radionuclides, or stable nuclides, and their compounds used in isotope tracing have the same chemical and biological properties as the corresponding common elements and their compounds in nature, but they have different nuclear physical properties. In conclusion, the introduction of isotope-labeled impurities allows for precise tracking and identification of molecules. From drug discovery to environmental studies, isotope labeling has become an essential tool for scientists worldwide.

Fig 1 Impurities

Uses of Labeled Impurities:

Isotopic labeling is a powerful technique used in various fields of science to study the behavior and characteristics of substances. It involves replacing one or more atoms of a molecule with their isotopic counterparts. The applications of isotope-labeled impurities are as follows:

--Environmental: By introducing a known amount of isotope-labeled impurities into a sample, researchers can study the fate and transport of these impurities in the environment. Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.

--Pharmaceutical: By incorporating isotope-labeled impurities into drug molecules, scientists can track the metabolism and elimination of these impurities in the human body. This information is crucial for assessing the safety and efficacy of drugs, as well as determining the potential toxic effects of impurities. In addition, isotopes are used for imaging, diagnosis, and newborn screening.

--Materials Science: Isotopic labeling is employed to study impurities in various materials. By introducing isotope-labeled impurities into a material, researchers can investigate their influence on the material's properties, such as conductivity, strength, and durability. This knowledge helps in optimizing material synthesis processes and improving the overall quality of materials.

--Food: By introducing isotope-labeled impurities into food products, scientists can track their movement and distribution during processing, storage, and consumption. This helps in ensuring the safety and quality of food products and aids in identifying potential sources of contamination.

Product Description:

Isotopes can be used to track the movement and change of substances. A method of studying organic reaction processes with the help of isotope atoms. That is, when isotopes are used to track the movement and change processes of substances, they are called tracer elements. The chemical properties of compounds labeled with tracer elements remain unchanged. Scientists can find out the detailed process of chemical reactions by tracing the compounds labeled by tracer elements. This scientific research method is called isotope labeling.

All Chemistry is committed to providing customers with isotope-labeled impurities. All Chemistry has a professional team, mature technology and purification technology, a rigorous working attitude, and strict quality requirements. We provide labeled impurities of high quality at a low price to all companies or institutions with R&D needs or quality control. All products come with comprehensive analytical data files and are of high chemical purity. According to customer requirements, provide corresponding isotope-labeled impurity products. We will adhere to the business philosophy of customer first, trying our best to meet customers' requirements for different purity isotope-labeled impurities.

Product Advantage:

ALL Chemistry is an integrated supply platform for stable isotopes, which can supply chemicals with stable isotopes such as deuterium D, carbon 13, oxygen 18 and nitrogen 15.

ALL Chemistry can provide some stable isotope-labeled impurities in stock, all products are provided with a quality analysis report (COA), and some products can provide NMR, MS, HPLC/GC spectra and detection methods.

ALL Chemistry provides isotope-labeled impurity products with the advantages of high sensitivity, simple location and accurate quantification.

ALL Chemistry provides isotope-labeled impurities with purity greater than 95%.

ALL Chemistry provides customized isotope-labeled impurity services to meet your requirements.

ALL Chemistry offers technical assistance and guidance in selecting the appropriate isotope-labeled impurities for your research.

Product Details:

ALL Chemistry can provide stable isotope-labeled impurities in stock, and some product information is as follows:

Fig 2 Ramifenazone-d7

Product Name: myo-Inositol-C-[d6]

Chemical Formula: C14H12D7N3O

CAS Number: 1330180-51-2

Purity: 95% by HPLC; 98% atom D

Please contact us for further information, including pricing, samples, and technical specifications. We look forward to providing our isotope-labeled impurity products. In addition, ALL Chemistry can provide synthesis and fine chemicals service if the existing products can't meet your needs, we expertise in synthesis of a broad array of customized molecules, and we offer lab scale custom synthesis, biosynthesis, bioconjugation and analytical services.

Custom Chemical Synthesis is the process where a molecule is made exclusively for a particular client according to specifications at their scale. It is one of the options available for pharmaceutical companies requiring active pharmaceutical ingredients (APIs), intermediates, fine chemicals, reference standards, impurities or metabolites needed to launch their research and development projects. We provide a seamless one stop process development service, effectively speeding up the process of new drug development and reducing overall costs. Available documents for custom synthesis projects: synthesis report, high-performance liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS), nuclear magnetic resonance analyses (NMR), etc.

Product List