Labeled Building Blocks


The Introduction of Labeled Building Blocks:


Building block is a general term for a class of compounds in chemistry. Building blocks mainly describe virtual compound fragments or compounds with active functional groups. The versatility and diversity of building blocks enable chemists to create a wide range of complex structures and materials. Common building blocks are mono-, bis-, and tri-functional compounds. Single-function units are mainly used as modifiers for core skeleton or end-cap compounds in linear compound library; Bi-functional molecular blocks can be used as junctions or bifurcation points; and Tri-functional molecular blocks are very useful skeleton molecules for constructing nonlinear compound libraries. Building blocks are the fundamental molecular units used in organic synthesis to construct more complex compounds. They provide the starting materials and precursors for the synthesis of pharmaceuticals, polymers, and specialty chemicals.

Isotope-labeled building blocks refer to replacing one or more atoms in molecular building blocks with stable isotopes. Isotope-labeled building blocks find applications in various fields, including drug discovery, metabolomics, proteomics, and environmental studies. Stable isotope-labeled building blocks have the advantages of high sensitivity, simple location, and accurate quantification. In conclusion, isotope-labeled building blocks are molecular units that incorporate isotopically labeled atoms. These specialized compounds enable precise tracking, analysis, and understanding of biological and chemical processes; isotope labeling promotes scientific progress.

Uses of Labeled Building Blocks:

--Application in Biochemical Field: Nuclear Magnetic Resonance (NMR) spectroscopy, a powerful technique for studying protein structure, relies on the incorporation of isotopically labeled amino acids into proteins. In the field of biomedicine, stable isotope-labeled building blocks could be used to overcome signal degradation during the detection of molecule structures by NMR. Building block analysis by NMR suffers from spectral overlap and line broadening; isotope-labeled building blocks could avoid these questions. By selectively replacing specific hydrogen atoms with deuterium or carbon atoms with carbon-13, researchers can obtain high-resolution NMR spectra, enabling the determination of protein structures and the elucidation of protein-protein interactions. In addition, isotope labeling has important applications in energy metabolism, localization and transportation of proteins in cells, drug discovery, and metabolite identification.

--Application in Environment: Application in Environment


Isotope-labeled building blocks are essential in studying biogeochemical cycling. Isotope labeled building blocks could be used to reveal microbially mediated carbon flow and carbon cycling processes. By introducing isotopically labeled nutrients or tracers into ecosystems, researchers can track their uptake, assimilation, and release by organisms, thus providing information on microbially mediated carbon flow and carbon cycling processes, and realizing the relationship between specific microbial communities and the carbon cycle they participate in. Isotope labeling enables the identification of key processes, such as nutrient cycling, carbon sequestration, and greenhouse gas emissions, providing insights into ecosystem functioning and nutrient dynamics. As technology advances, the use of isotope-labeled building blocks will continue to provide valuable insights into the complex interactions between human activities and the environment.


Product Description:


When isotopes are used to track the movement and change processes of substances, they are called tracer elements. The chemical properties of compounds labeled with tracer elements remain unchanged. Scientists can find out the detailed process of chemical reactions by tracing the compounds labeled by tracer elements. This scientific research method is called isotope labeling. The isotope labeling method is also called the isotope tracer method. Stable Isotopes are stable isotope compounds, ranging from gases to complex molecules. These compounds are useful for tracer studies in proteomics and metabolomics, agents for MRI and MRS, and a wide range of other biomedical applications.

ALL Chemistry is committed to providing customers with isotope-labeled building blocks. We offer a complete range of labeled building blocks standards. All products come with comprehensive analytical data files and are of high chemical purity. These specialized compounds, enriched with stable isotopes, serve as essential tools for studying organic synthesis, drug discovery, materials science, and many other chemical disciplines. With our isotopically labeled building blocks, researchers can have a better understanding of complex chemistry.

Product Advantage:


ALL Chemistry is an integrated supply platform for stable isotopes, which can supply chemicals with stable isotopes such as deuterium D, carbon 13, oxygen 18 and nitrogen 15.

ALL Chemistry can provide some stable isotope-labeled building blocks in stock, all products are provided with a quality analysis report (COA), and some products can provide NMR, MS, HPLC/GC spectra and detection methods.

ALL Chemistry provides isotopically labeled building blocks products with the advantages of high sensitivity, simple location and accurate quantification.

ALL Chemistry provides isotopically labeled building blocks with purity greater than 95%.

ALL Chemistry provides customized isotope-labeled building block services to meet your requirements.

ALL chemistry provides technical assistance, guidance and help you choose the appropriate isotope-labeled building blocks for your research.


Product Details:


Fig 2 1-Methyl-4-piperidone-[2,2,6,6-d4]

Product Name: 1-Methyl-4-piperidone-[2,2,6,6-d4]

Chemical Formula: C6H7D4NO

CAS Number: 1189723-14-5

Purity: ≥95%

Please contact us for further information, including pricing, samples, and technical specifications. We look forward to providing our isotope-labeled building block products. In addition, ALL Chemistry can provide synthesis and fine chemicals service if the existing products can't meet your needs, we have expertise in synthesis of a broad array of customized molecules, and we offer lab scale custom synthesis, biosynthesis, bioconjugation and analytical services.

Custom Chemical Synthesis is the process where a molecule is made exclusively for a particular client according to specifications at their scale. It is one of the options available for pharmaceutical companies requiring active pharmaceutical ingredients (APIs), intermediates, fine chemicals, reference standards, impurities or metabolites needed to launch their research and development projects. We provide a seamless one-stop process development service, effectively speeding up the process of new drug development and reducing overall costs. Available documents for custom synthesis projects: synthesis report, high-performance liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS), nuclear magnetic resonance analyses (NMR), etc.

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