Labeled Carbohydrates


The Introduction of Labeled Carbohydrates:


Carbohydrates, also known as sugars, are a class of biomolecules composed of C, H, and O elements. It is the most abundant organic compound with broad-spectrum chemical structure and biological functions in nature. Because it contains two to one hydrogen and oxygen, just like water, it is called carbohydrate. In terms of the chemical structure, carbohydrates are polyhydroxy aldehydes, polyhydroxy ketones, or compounds that can hydrolyze to polyhydroxy aldehydes and polyhydroxy ketones. Carbohydrates in food are divided into two categories: effective carbohydrates that people can absorb and utilize and ineffective carbohydrates that people can't digest. As one of the indispensable components, carbohydrates play an irreplaceable role in the health of human bodies and the regular conduct of life activities. Carbohydrate is the main source of energy needed by all organisms to maintain life activities. It is not only a nutrient, but also some of them have special physiological activities.

Glucose metabolism plays an important role in various biochemical processes. Glucose metabolism refers to decomposing sugars into small molecular substances, converting small molecular substances into sugars, and synthesizing disaccharides and polysaccharides from monosaccharides. Isotopically labeled carbohydrates are specialized compounds in which specific atoms within the carbohydrate molecule are replaced with their isotopically labeled counterparts. Isotopically labeled carbohydrates find applications in metabolic studies, nutrition research, and drug development, providing insights into carbohydrate metabolism and its impact on various biological processes.



Fig 1 Carbohydrates

Uses of Labeled Carbohydrates:


Isotopically labeled carbohydrates could be used to study carbohydrate metabolism. These specialized compounds provide a unique tool for tracing the behavior of carbohydrates within living organisms. Isotope-labeled carbohydrates can  reveal quantitative and qualitative analysis of carbohydrates and substances related to metabolism pathways. Isotope-labeled carbohydrates contribute to advancements in metabolic research, glycobiology, nutrition science, and drug development, aiding in the understanding of carbohydrate metabolism and its implications in health and disease.

Stable isotope tracer metabonomics has been widely used in glucose catabolism. Researchers labeled the precursors of glucose catabolism with 13C, and obtained the specific metabolic pathways and potential drug targets of glucose catabolism disorders through quantitative analysis of the isotopic distribution of its downstream metabolites. It is of great significance to study the understanding of glucose catabolism on the etiology of related diseases and the development of drugs to delay or treat diseases. It is still difficult to detect the specific process of metabolites by traditional metabonomics, and even if the metabolites related to glucose catabolism are detected to be disordered, it is impossible to determine their specific metabolic pathways and drug targets. Stable isotope tracer metabonomics can make up for the defect that traditional metabonomics can only detect the total amount of terminal metabolites, but it can't distinguish which metabolic pathway the metabolites come from.


Product Description:


Isotopes can be used to track the movement and change of substances. A method of studying organic reaction process with the help of isotope atoms. That is, when isotopes are used to track the movement and change process of substances, they are called tracer elements The chemical properties of compounds labeled with tracer elements remain unchanged. Scientists can find out the detailed process of chemical reactions by tracing the compounds labeled by tracer elements. This scientific research method is called isotope labeling.

ALL Chemistry is committed to providing customers with isotope-labeled carbohydrates. We offer a complete range of labeled carbohydrates standards. With uncompromising quality, stable isotope enrichment, and customization options, our labeled carbohydrates provide precise tracking and quantification capabilities in various chemical disciplines. The carbohydrate products ALL Chemistry provides include isotope labeled glucose, fructose, mannose, galactose, sucrose, fucose, xylose, threose and derivatives. This product is only used for scientific research, please contact us if necessary.

Product Advantage:


ALL Chemistry is an integrated supply platform for stable isotopes, which can supply chemicals with stable isotopes such as deuterium D, carbon 13, oxygen 18 and nitrogen 15.

ALL Chemistry can provide some stable isotope-labeled carbohydrates in stock, all products are provided with a quality analysis report (COA), and some products can provide NMR, MS, HPLC/GC spectra and detection methods.

ALL Chemistry provides isotopically labeled carbohydrates products with the advantages of high sensitivity, simple location and accurate quantification.

ALL Chemistry provides isotopically labeled carbohydrates with purity greater than 95%.

ALL Chemistry provides customized isotope-labeled carbohydrates services to meet your requirements.

ALL Chemistry offers technical assistance, guidance in selecting the appropriate isotopically labeled carbohydrates for your research.


Product Details:


ALL Chemistry can provide stable isotope-labeled amino acids in stock, and some product information is as follows:


Fig 2 myo-Inositol-C-[d6]

Product Name: myo-Inositol-C-[d6]

Chemical Formula: C6H6D6O6

CAS Number: 68922-44-1

Purity: ≥95%

Appearance: White to Off-White Solid


Please contact us for further information, including pricing, samples, and technical specifications. We look forward to providing our isotope-labeled carbohydrate products. In addition, ALL Chemistry can provide synthesis and fine chemicals service if the existing products can't meet your needs, we expertise in synthesis of a broad array of customized molecules, and we offer lab scale custom synthesis, biosynthesis, bioconjugation and analytical services.

Custom Chemical Synthesis is the process where a molecule is made exclusively for a particular client according to specifications at their scale. It is one of the options available for pharmaceutical companies requiring active pharmaceutical ingredients (APIs), intermediates, fine chemicals, reference standards, impurities or metabolites needed to launch their research and development projects. We provide a seamless one stop process development service, effectively speeding up the process of new drug development and reducing overall costs. Available documents for custom synthesis projects: synthesis report, high-performance liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS), nuclear magnetic resonance analyses (NMR), etc.

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