Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine

Datasheet MSDS
Catalog Number
RP0045
Product Name
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
Structure
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
CAS Number
175724-30-8
IUPAC Name
tert-butyl 3-[2-amino-3-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]-2-[[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]methyl]propoxy]propanoate
Synonyms
Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane; tert-butyl 3,3'-(2-amino-2-((3-tert-butoxy-3-oxopropoxy)methyl)propane-1,3-diyl)bis(oxy)dipropanoate
Molecular Formula
C25H47NO9
Molecular Weight
505.64
Appearance
Colourless oil
Purity
>98.0%
Solubility
10 mm in DMSO
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Description
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
SMILES
CC(C)(C)OC(=O)CCOCC(COCCC(=O)OC(C)(C)C)(COCCC(=O)OC(C)(C)C)N
InChI
InChI=1S/C25H47NO9/c1-22(2,3)33-19(27)10-13-30-16-25(26,17-31-14-11-20(28)34-23(4,5)6)18-32-15-12-21(29)35-24(7,8)9/h10-18,26H2,1-9H3
InChI Key
KPXODPHVWBQJEG-UHFFFAOYSA-N
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