Aprepitant

Datasheet MSDS
Catalog Number
A1743
Product Name
Aprepitant
CAS Number
170729-80-3
Synonyms
L-754030 , MK-869 , MK-0869 , Aprepitant`
Molecular Formula
C23H21F7N4O3
Molecular Weight
534.43
Purity
99.90%
Solubility
DMSO: 99 mg/mL (185.2 mM) Ethanol: 12 mg/mL (22.5 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Aprepitant is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer.
Target
NK1
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