Dolutegravir

Datasheet MSDS
Catalog Number
A6198
Product Name
Dolutegravir
Structure
Dolutegravir
CAS Number
1051375-16-6
Synonyms
GSK1349572, S/GSK1349572, S/GSK1349572, GSK1349572
Molecular Formula
C20H19F2N3O5
Molecular Weight
419.38
Purity
99.08%
Solubility
DMSO: 77 mg/mL (183.6 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Dolutegravir (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Target
HIV integrase
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