Terpenoids

 

The Introduction of Terpenoids:

 

The terpenoids (aka isoprenoids) are a large (estimated 60% of known natural products ) and diverse group of lipids derived from five-carbon isoprene units assembled in thousands of combinations. Terpenoids are the largest group of phytochemicals consisting of several diverse compounds that are highly diverse in chemical structure and are a rich reservoir of candidate compounds for drug discovery. Most terpenoids are multicyclic structures that differ from one another not only in functional groups but also in their basic carbon skeletons.

Terpenoids are ubiquitous, thus, they are found in almost all classes of living organisms. They contribute to the flavor, scents, and color of plants' leaves, flowers, and fruits.

While we can identify isoprene units within a terpenoid structure and use that in its classification, the building block for terpenoid synthesis in nature is isopentenyl diphosphate. There are two major routes to the synthesis of IPP: (1) the mevalonate pathway and (2) the 1-deoxyxylulose pathway. Terpenoids show a range of pharmacological activities, such as anti-viral, hypoglycemic, anti-bacterial, anti-malarial, anti-inflammatory, and anti-cancer activities. Terpenoids are also essential for plant growth and development. The terpenoids produced by plants not only protect them against insects and herbivores but also protect from fungal diseases and infestations, whereas, in animals, terpenoids serve as the precursors of steroids and sterols.

 

Fig 1 Terpenoids

Classification of Terpenoids:

 

Over a dozen naturally originated terpenoid compounds, in particular those derived from traditional Chinese medicine, were classified into five categories according to the structures, namely monoterpenoids, sesquiterpenoids, diterpenoids, triterpenoids and others. These subclassifications can be further classified according to different skeletons.

--Monoterpenoids: Monoterpenes and monoterpenoids represent a set of chemicals widely diffused in plants whose basic structure consists of two linked isoprene units. The monoterpenoids are formed by the addition of an alcoholic group to the monoterpene structure. Monoterpenoids are distributed in higher plants, algae, fungi, and even some insects and mammals, but they are very rare in mosses, ferns, and lichens. Characteristic features of monoterpenoids are their volatility and intensely pungent odors, and they are the most common components in plants responsible for fragrance and flavor. Monoterpenoids now appear as the one group of arthropod natural products for which knowledge of their biochemical, physiological, and ecological roles is most complete. To date, the two most well-studied examples are the iridoid monoterpenoids associated with Chrysomelid beetles and monoterpenes associated with bark beetles. 

--Sesquiterpenoids: Sesquiterpenoids are a class of enormously diverse natural products derived from three isoprene units and exist in a wide variety of forms, including linear, monocyclic, bicyclic, and tricyclic frameworks. Sesquiterpenoids are arguably the richest natural products from plants and microorganisms. Today, thousands of sesquiterpenoids have been discovered, with more than 100 skeleton types. The chemical diversity of sesquiterpenoids starts with the diverse sesquiterpene hydrocarbon backbones, which are created by carbocation cascade reactions programmed in sesquiterpene synthases (STSs). Sesquiterpenoids, with abundant structural skeleton types and a wide range of bioactivities, are considered good candidates to be antibacterial and antifungal agents. In the past decades, many sesquiterpenoids have been isolated from plants and fungi that exhibit good antibacterial and antifungal activities.

--Diterpenoids: Diterpenoids are chemical compounds containing 20 carbon atoms and belong to the terpenoid class. They derive from geranylgeraniol, a C20 precursor, have a C20H32 basic structure, and are composed of four isoprene units. Diterpenoids can be classified as linear, bicyclic, tricyclic, tetracyclic, pentacyclic, or macrocyclic diterpenes depending on their skeletal core. Diterpenoids (diterpenes) occur in many plants used for their reputed medicinal properties and have been of interest as potential phytopharmaceuticals in the form of standardized plant extracts. Many plants produce diterpenoids as secondary metabolites, which serve various biological functions. These compounds often contribute to the plant's defense mechanisms against herbivores, pests, and pathogens. One of the most widely investigated phytopharmaceuticals is Ginkgo biloba, which has produced promising outcomes on memory and cognitive functions in numerous clinical studies.

--Triterpenoids: Triterpenoids are a large group of natural products derived from C30 precursors. The triterpenoids group displays well over 100 distinct skeletons. This class of natural products includes triterpenes, steroids, limonoids, quassinoids, and triterpenoidal and steroidal saponins. Triterpenoids, which extract from Sympcocos Racenosa, are a group of Terpenes (isoprenoids) are defined as terpenoid derviatives of triterpene molecules. The triterpenoids are formed biosynthetically from six isoprene units and share in common the C30 acyclic precursor squalene. Different types of ring closure in squalene can give rise to many different skeletal types of triterpenoids. Over 4000 natural triterpenoids have been isolated, and more than 40 skeletal types have been identified. Triterpenoids are cyclized from oxidized squalene precursors by oxidosqualene cyclases, creating more than 100 different cyclical triterpene scaffolds.

 

Product Description:

 

Terpenes are a class of organic compounds, produced by a variety of plants and some insects. These compounds are derived biosynthetically from units of isoprene. Terpenes (hydrocarbons) containing additional functional groups are called terpenoids. Terpenoids play a crucial role in numerous biological processes and possess remarkable chemical properties that make them invaluable in the field of chemistry. These terpenoids provided by ALL Chemistry can be utilized in a multitude of experiments, including organic synthesis, drug discovery, natural product analysis, and more. Their unique chemical makeup enables researchers to explore their potential as building blocks for novel drug molecules, as well as study their interactions with enzymes, receptors, and other biological targets.

Furthermore, ALL Chemistry's terpenoids exhibit exceptional versatility, making them suitable for a broad range of research areas such as medicinal chemistry, biochemistry, and materials science. Whether you are investigating the medicinal properties of terpenoids, developing new materials with enhanced properties, or studying their ecological roles, ALL Chemistry's product provides an indispensable resource for your scientific endeavors. Choose our terpenoids for ALL Chemistry to unlock the potential of these remarkable organic compounds and advance your scientific discoveries. Explore the world of terpenoids today and embark on a journey of groundbreaking research.

 

Product Category

CAS Number

Product Name

Purity

Molecular Formula

Terpenoids

144-68-3

Zeaxanthin

95%

C40H56O2

Terpenoids

77844-93-0

Euglobal Ia1

92.00%

C23H30O5

Terpenoids

6983-79-5

Bixin

98%

C25H30O4

Terpenoids

61955-76-8

9-Hydroxythymol

97.50%

C10H14O2

Terpenoids

61570-82-9

3-Hydroxy-p-menth-1-en-6-one

96.50%

C10H16O2

Terpenoids

6138-88-1

Naginata ketone

95%

C10H12O2

Terpenoids

596-85-0

Manool

95%

C20H34O

Terpenoids

547-17-1

Lutein palmitate stearate

>95%

C74H124O6

Terpenoids

5451-67-2

Thymol isobutyrate

98.00%

C14H20O2

Terpenoids

491613-65-1

Dicliripariside A

98.00%

C32H48O14

 

Please contact us for further information if you have a purchase requirement, including pricing, samples, and technical specifications. We look forward to providing our terpenoid products. In addition, ALL Chemistry provides a seamless one-stop process development service, ALL Chemistry can provide synthesis and fine chemical services if the existing products can't meet your needs, we have expertise in the synthesis of a broad array of customized molecules, and we offer lab scale custom synthesis, biosynthesis, bioconjugation and analytical services.

 

Product Advantage:

 

Provide quality-guaranteed products, all products are provided with a quality analysis report (COA), use advanced instruments such as MS(Mass Spectrometry), HPLC and NMR (Nuclear Magnetic Resonance) for quality inspection.

Professional and reliable packaging ensures the safety and stability of products from transportation, storage to use.

ALL Chemistry provides terpenoid products with a purity greater than 95%.

ALL Chemistry guarantees the confidence to put our products in a risk-free environment for worldwide scientists and researchers.

Access our expertise and technical support from anywhere, anytime.

 

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