Isotopic labeling is a technique used to track the passage of an isotope (variants of a particular chemical element that differ in neutron number) through a reaction, metabolic pathway, or cell. The nuclides used in isotopic labeling may be stable nuclides or radionuclides, which the former labeling is called stable isotope labeling. Stable isotope labeling can act as a tracers used to model several chemical and biochemical systems, because the chosen isotope can be identified through nuclear magnetic resonance (NMR) and mass spectrometry (MS). For example, the position of the isotopes in the products is measured to determine the sequence the isotopic atom followed in the reaction or the cell's metabolic pathway[1]. The labeled products can be obtained by replacing specific atoms with their isotope. Some of the most common stable isotopes are 2H, 13C, and 15N. There is a wide range of compounds that can be custom labeled with stable isotopes, including: NMR solvents, amino acids, nucleic acids, lipids, common metabolites and cell growth media, etc.
ALL Chemistry Inc. offers high-quality custom stable isotope labeling services that you can specify the types of stable isotopes, the percentage of labeled isotopes and the specifically labeled positions on the compound. Our customers’ needs are met by using advanced processes, stringent quality specifications and specially designed laboratories.
Our Advantages
* Isotopic Labeling Service (2H, 13C, 15N, 18O and Others (please inquire))
* Completed analytical data packages (COA, NMR, UPLC-MS and IR, etc.)
* Custom services to match your study requirements
* Synthesis report in the agreed format
* Additional services: Storage, Repurification and Re-analysis, etc.
* Small- and Large-Scale Chemistry Capabilities
* Cost-Effectiveness and High Efficiency
ALL Chemistry Inc. also is an innovator and manufacturer for stable isotope labeled materials in the industry, offering an extensive labeled product catalog including Labelled Amino Acids, Labelled APIs, Labelled Building Blocks, Labelled Carbohydrates, Labelled Impurities and Labelled Peptides. All the compounds mentioned above are in stock and ready to ship.
ALL Chemistry Inc. aims to provide global customers with professional chemical products and custom solutions. If you are interested in our products or services, please contact us. Our R&D scientists will make a detailed plan and technical support manager will prepare a quotation for you.
References
[1] Ferrara, M., 12 - Future perspectives for metabolomics in nutrition research: a nutritionist’s view, in Metabolomics as a Tool in Nutrition Research, J.L. Sébédio and L. Brennan, J.L. Sébédio and L. Brennan^Editors. 2015, Woodhead Publishing. p. 231-236.
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