Diterpenoids - ALL Chemistry-Custom Chemical Solutions Supplier

Diterpenoids

The Introduction of Diterpenoids:

Diterpenoids are chemical compounds containing 20 carbon atoms and belong to the terpenoid class. They derive from geranylgeraniol, a C20 precursor, have a C20H32 basic structure, and are composed of four isoprene units. Diterpenoids can be classified as linear, bicyclic, tricyclic, tetracyclic, pentacyclic, or macrocyclic diterpenes depending on their skeletal core. Diterpenoids (diterpenes) occur in many plants used for their reputed medicinal properties and have been of interest as potential phytopharmaceuticals in the form of standardized plant extracts. Many plants produce diterpenoids as secondary metabolites, which serve various biological functions. These compounds often contribute to the plant's defense mechanisms against herbivores, pests, and pathogens. One of the most widely investigated phytopharmaceuticals is Ginkgo biloba, which has produced promising outcomes on memory and cognitive functions in numerous clinical studies.

Diterpenoid natural products cover a vast chemical diversity and include many medicinally and industrially relevant compounds. A diterpenoid molecule may also include alcohol, phenol, aldehyde, cheton, or acidic functional groups. These compounds are highly lipophilic, odorless, and may possess strong flavours. They are found mainly in fungi and in resins of higher-order plants, as typical products of plant metabolism. Diterpenoids are a diverse class of natural compounds that play important roles in various biological processes. Their presence in plants, fungi, and marine organisms highlights their significance in nature. The pharmacological properties exhibited by diterpenoids make them promising candidates for the development of new drugs. Further research into the biosynthesis, isolation, and characterization of diterpenoids will undoubtedly contribute to our understanding of their biological functions and potential applications in medicine.

Fig 1 Novaxenicin A

Classification of Diterpenoids:

--Bicyclic Diterpenoids: Bicyclic diterpenoids are characterized by their two fused rings, they exhibit a wide range of biological activities and have been extensively studied for their pharmacological properties. Clerodane diterpenes are the natural group of secondary metabolites holding the utmost pharmacological significance. These are bicyclic structures consisting of a fused ring (decalin moiety from C-1 to C-10) with a six-carbon side chain (C-11 to C-16) attached at C-9. The labdane-related diterpenoids are a special group, consisting of over 7000 members, which are distinguished by their unique biosynthesis.

--Tricyclic Diterpenoids: Tricyclic diterpenoids, as the name suggests, contain three fused rings. They are often found in plants and have been used in traditional medicine for centuries. Abietane is a class of diterpenoids with excellent metabolic profile. Compounds of this class showed broad-spectrum antiviral, antibacterial, and antifungal activity. The abietatriene lactones are a group of compounds that possess an oxygen-containing ring that predominantly is in the form of lactones (i.e., abietatrien-20,7-olides). This group of abietanes are exemplified by carnosol (11,12-dihydroxy-8,11,13-20,7-olide).

--Tetracyclic Diterpenoids: Tetracyclic diterpenoids contain four fused rings, making them structurally more complex. They are commonly found in plants and marine organisms. Cyathus is a genus of fungi in the Nidulariaceae, a family collectively known as the bird’s nest fungi. Such compounds are named so, as they resemble tiny bird’s nests filled with “eggs,” structures large enough to have been mistaken in the past for seeds. Indole diterpenes are a broad class of secondary metabolites with enormous structural and functional diversity. They mostly occur in filamentous fungal members having the most abundance in Penicillium, Aspergillus, Neotyphodium, and Claviceps.

Bicyclic, tricyclic, and tetracyclic diterpenoids represent an important class of natural compounds with diverse biological activities. Their presence in plants, fungi, and marine organisms highlights their significance in nature. The pharmacological properties exhibited by these diterpenoids make them promising candidates for the development of new drugs. Continued research into these compounds will contribute to our knowledge of their biological roles and potential therapeutic applications.

Product Description:

Diterpenoids are a class of natural compounds that offer a wide array of applications in various industries, including pharmaceuticals, cosmetics, and agriculture. Our collection includes an extensive selection of bicyclic, tricyclic, and tetracyclic diterpenoids, each possessing unique chemical structures and functional groups. These compounds have been carefully isolated and purified from natural sources, ensuring their authenticity and efficacy. ALL Chemistry provides diterpenoids related products with a wide range of sources.

At ALL Chemistry, we prioritize quality and customer satisfaction. Our diterpenoid products undergo rigorous testing and quality control measures to ensure their purity, potency, and consistency. We provide comprehensive technical support and documentation, including certificates of analysis and safety data sheets, to assist our customers in their research and development endeavors. Whether you are a researcher, formulator, or manufacturer in the pharmaceutical, cosmetic, or agricultural industry, our diterpenoid products are designed to meet your specific needs. Experience the versatility and potential of diterpenoids in your applications with our reliable and premium-quality products.

Partial Product Details:

Product Category	CAS Number	Product Name	Purity
Diterpenoids	94529-97-2	20-Deoxocarnosol	>98%
Diterpenoids	952473-86-8	Neocaesalpin L	>97%
Diterpenoids	83150-97-4	Carpalasionin	>95%
Diterpenoids	78536-37-5	Excisanin A	>95%
Diterpenoids	887333-30-4	Hebeirubescensin H	>95%
Diterpenoids	75567-38-3	20-Deoxyingenol 3-angelate	>98%
Diterpenoids	66556-91-0	ent-3β-Hydroxykaur-16-en-19-oic acid	97.50%
Diterpenoids	63768-17-2	12α-Hydroxygrandiflorenic acid	>97%
Diterpenoids	73483-88-2	Tetrachyrin	>95%
Diterpenoids	76376-43-7	Euphorbia factor L1	≥98%

Please contact us for further information if you have a purchase requirement, including pricing, samples, and technical specifications. We look forward to providing our diterpenoid products. In addition, ALL Chemistry provides a seamless one-stop process development service, ALL Chemistry can provide synthesis and fine chemical services if the existing products can't meet your needs, we have expertise in the synthesis of a broad array of customized molecules, and we offer lab scale custom synthesis, biosynthesis, bioconjugation and analytical services.

Product Advantage:

Provide quality-guaranteed products, all products are provided with a quality analysis report (COA), use advanced instruments such as MS(Mass Spectrometry), HPLC and NMR (Nuclear Magnetic Resonance) for quality inspection.

Professional and reliable packaging ensures the safety and stability of products from transportation, storage to use.

ALL Chemistry provides diterpenoid products with a purity greater than 95%.

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