The Introduction of Phenols:

 

Phenol, is any of a family of organic compounds characterized by a hydroxyl (―OH) group attached to a carbon atom that is part of an aromatic ring. Besides serving as the generic name for the entire family, the term phenol is also the specific name for its simplest member, monohydroxybenzene (C6H5OH), also known as benzenol or carbolic acid. Phenols are similar to alcohol but form stronger hydrogen bonds. Thus, they are more soluble in water than alcohol and have higher boiling points.  Phenols are stronger acids than alcohols, but they are still quite weak acids. Phenols occur either as colorless liquids or white solids at room temperature and may be highly toxic and caustic. Many phenolic compounds were discovered and used long before chemists were able to determine their structures. Therefore, trivial names (i.e., vanillin, salicylic acid, pyrocatechol, resorcinol, cresol, hydroquinone, and eugenol) are often used for the most common phenolic compounds.

Phenol was first extracted from coal tar, but now it is produced on a large scale by industrial processes starting with crude oil. Phenol is famous as a precursor to many materials and useful compounds, such as phenolic resins, plastics, and related materials. Phenolic compounds are produced by plants and microorganisms. Because they are widely found in food and plants in the human diet, their functions in human health and diseases have been widely studied. Some phenolic compounds have a bactericidal effect and are used to prepare disinfectants. Other phenols have antioxidant, estrogenic, or endocrine-disrupting activities. Phenols are used in the aviation industry and in other chemically resistant coatings. Phenol derivatives are also used in the preparation of cosmetics. It is also used in the manufacture of explosives, fertilizers, paints, rubber, textiles, adhesives, pharmaceuticals, paper, soap, and wood preservatives.

 

Fig 1 Phenol

Classification of Phenols:

 

According to the number of phenol rings and the structural elements that bind rings to one another, phenolic compounds are grouped and classified as simple phenols, phenolic acids, flavonoids, xanthones, stilbenes, and lignans.

--Simple Phenols: Simple phenols are described as compounds having at least one hydroxyl group attached to an aromatic ring as a basic skeleton. These compounds are widely distributed in nature and can be found in various plant sources such as fruits, vegetables, and herbs. Simple phenols are known for their antioxidant properties and have been studied for their potential health benefits, including their ability to protect against oxidative stress and inflammation.

--Phenolic Acids: Phenolic acids, also known as phenol carboxylic acids, are aromatic acids that contain a phenolic ring and a carboxyl functional group. Phenolic acids are major components of berries. Phenolic acids are represented by cinnamic and benzoic acid derivatives. Salicylic acid is one of the simplest phenolic acids. Phenolic acids are known for their antioxidant and anti-inflammatory properties, and they have been shown to have potential benefits for cardiovascular health, diabetes management, and cancer prevention.

--Flavonoids: Flavonoids and phenolic acids constitute one of the most widespread groups of plant phenolics. Because of their significance in plants and human health, a deeper understanding of flavonoid concentration and biological activities may suggest their potential as therapeutic agents, as well as predicting and monitoring the quality of medicinal herbs. Flavonoids are known for their strong antioxidant and anti-inflammatory properties, and they have been studied for their potential effects on cardiovascular health, cancer prevention, and cognitive function.

--Xanthones:  Xanthones are a group of natural products with interesting pharmaceutical properties, and the majority occur in two plant families (Gentianaceae and Hypericaceae). It appears that most xanthones identified so far in plants of the continent were isolated from the family Guttiferae.

--Stilbenes: Stilbenes are some of the important phenolic compounds originating from plant families like Vitaceae, Leguminaceae, Gnetaceae, and Dipterocarpaceae. Structurally, they have a C6–C2–C6 skeleton, usually with two isomeric forms. Stilbenes are biosynthesized due to biotic and abiotic stresses such as microbial infections, high temperatures, and oxidation. Resveratrol, found in grapes and red wine, is one of the most well-known stilbenes.

--Lignans: Lignans are chemical compounds, defined as phytoestrogens, found in plants. Lignans are phenolic dimers possessing a 2,3-dibenzylbutane structure. Such compounds are known to exist as minor constituents of many plants, where they form the building blocks for the formation of lignin in the plant cell wall. Plant lignans are polyphenols derived from phenylanaline, and can be metabolized by intestinal bacteria to form mammalian lignans such as enerodiol and enterolactone. 

 

Product Description:

 

Phenols are known for their exceptional antioxidant properties, making them valuable in the formulation of skincare and personal care products. They protect the skin from harmful free radicals, preventing premature aging and maintaining a youthful complexion. ALL Chemistry phenol products deliver superior antioxidant benefits and promote healthy, radiant skin.

 

Product Category

CAS Number

Product Name

Purity

Molecular Formula

Phenols

555-66-8

6-Shogaol

≥99%

C17H24O3

Phenols

23513-14-6

Gingerol

≥98%

C17H26O4

Phenols

501-36-0

Resveratrol

≥98%

C14H12O3

Phenols

500-66-3

Olivetol

≥98%

C11H16O2

Phenols

54-28-4

γ-Tocopherol

≥96%

C28H48O2

Phenols

623-05-2

4-Hydroxybenzyl alcohol

≥98%

C7H8O2

Phenols

62218-08-0

ε-Viniferin

≥96%

C28H22O6

Phenols

149-91-7

Gallic acid

≥99%

C7H6O5

Phenols

29700-22-9

Oxyresveratrol

0.98

C14H12O4

Phenols

537-42-8

Pterostilbene

>98%

C16H16O3

Please contact us for further information if you have a purchase requirement, including pricing, samples, and technical specifications. We look forward to providing our phenol products. In addition, ALL Chemistry provides a seamless one-stop process development service, ALL Chemistry can provide synthesis and fine chemical services if the existing products can't meet your needs, we have expertise in the synthesis of a broad array of customized molecules, and we offer lab scale custom synthesis, biosynthesis, bioconjugation and analytical services.

Product Advantage:

 

Provide quality-guaranteed products, all products are provided with a quality analysis report (COA), use advanced instruments such as MS(Mass Spectrometry), HPLC and NMR (Nuclear Magnetic Resonance) for quality inspection.

Professional and reliable packaging ensures the safety and stability of products from transportation, storage to use.

ALL Chemistry provides phenol products with a purity greater than 95%.

ALL Chemistry guarantees the confidence to put our products  in a risk-free environment for worldwide scientists and researchers.

Access our expertise and technical support from anywhere, anytime.

 

Product List