Flavonoids - ALL Chemistry-Custom Chemical Solutions Supplier

Flavonoids

The Introduction of Flavonoids:

Flavonoids, also known as flavones, are a class of nonnitrogenous biological pigments that are widely found in plants.The word ‘flavonoid’ is derived from the Latin word flavus meaning yellow and many flavonoids are indeed yellow in color. Flavonoids are a ubiquitous group of naturally occurring polyphenolic compounds characterized by the flavan nucleus and represent one of the most prevalent classes of compounds in fruits, vegetables and plant-derived beverages. Flavonoids are now known to be ubiquitous in many plants, including the onion (Allium cepa) skin is used as a hay-fever remedy and a digestive anti-inflammatory, and are the active ingredient in a popular OTC nasal spray for sinusitis and allergies. Flavonoids are water-soluble phenolic compounds (having a -OH group attached to an aromatic ring) and are found in the vacuoles of plant cells. Quercetin and rutin are among the most largely found flavonoids in a great variety of fruits and vegetables, including tea, coffee, and other grains.

The biological activities of flavonoids have been demonstrated as anti-inflammatory, antihepatotoxic, antitumor, antimicrobial, antiviral, enzyme inhibitors, and antioxidant, and as having central vascular effects. Their ability to scavenge free radicals and reduce oxidative stress has been linked to various health benefits, such as reducing the risk of chronic diseases, including cardiovascular diseases, cancer, and neurodegenerative disorders. Flavonoids are a diverse group of natural compounds found in plants and foods that offer a multitude of health benefits. Their structural diversity and biological activities make them valuable components of a balanced diet and potential candidates for the development of pharmaceuticals and functional foods. Continued research into the bioavailability, metabolism, and mechanisms of action of flavonoids will undoubtedly contribute to our understanding of their potential applications in promoting human health and well-being.

Classification of Flavonoids:

Flavonoids can be subdivided into different subgroups depending on the carbon of the C ring on which the B ring is attached and the degree of unsaturation and oxidation of the C ring (Fig. 1). Flavonoids in which the B ring is linked in position 2 can be further subdivided into several subgroups based on the structural features of the C ring. These subgroups are flavones, flavonols, flavanones, flavanonols, flavanols or catechins, anthocyanins and chalcones.

--Flavones: Flavones are one of the important subgroups of flavonoids. Flavones are widely present in leaves, flowers and fruits as glucosides. Celery, parsley, red peppers, chamomile, mint and ginkgo biloba are among the major sources of flavones.

--Flavonols: Flavonols are flavonoids with a ketone group. They are building blocks of proanthocyanins. Flavonols occur abundantly in a variety of fruits and vegetables.

--Flavanones: Flavanones are another important class which is generally present in all citrus fruits such as oranges, lemons and grapes. Hesperitin, naringenin and eriodictyol are examples of this class of flavonoids

--Isoflavonoids: Isoflavonoids are a large and very distinctive subgroup of flavonoids. Isoflavonoids enjoy only a limited distribution in the plant kingdom and are predominantly found in soyabeans and other leguminous plants.

--Neoflavonoids: Neoflavonoids are a class of polyphenolic compounds. While flavonoids have a 2-phenylchromen-4-one backbone, neoflavonoids have a 4-phenylchromen backbone with no hydroxyl group substitution at position 2.

--Flavanols, Flavan-3-ols or Catechins: Flavanonols, also called dihydroflavonols or catechins, are the 3-hydroxy derivatives of flavanones.

--Anthocyanins: Anthocyanins are pigments responsible for colors in plants, flowers and fruits. Cyanidin, delphinidin, malvidin, pelargonidin and peonidin are the most commonly studied anthocyanins

--Chalcones: Chalcones are a subclass of flavonoids. They are characterized by the absence of ‘ring C’ of the basic flavonoid skeleton structure shown in Fig. 1. Hence, they can also be referred to as open-chain flavonoids.

Fig 1 Basic Skeleton Structure of Flavonoids and Their Classes

Product Description:

Flavonoids are a group of polyphenolic natural products, with over 5,000 different members. Our collection encompasses a diverse selection of flavonoid subclasses, including flavones, flavonols, flavanones, flavanols, anthocyanins, and isoflavones. Each subclass offers unique chemical structures and functional groups, allowing for a wide range of applications and benefits. Flavonoids act as allelochemicals and as anti-microbial and anti-herbivory factors. Flavonoids and their metabolites have been ascribed to positive effects on human and animal health and are central to the current interest in “botanicals” for disease therapy and chemoprevention. Current roles in health support include antioxidant, anti-inflammatory and cardiovascular benefits, in addition to possible positive effects in the treatments of certain cancers.

At ALL Chemistry, we prioritize quality and customer satisfaction. Our flavonoid products undergo rigorous testing and quality control measures to ensure their purity, potency, and consistency. We provide comprehensive technical support and documentation, including certificates of analysis and safety data sheets, to assist our customers in their research and development endeavors. Whether you are a researcher, formulator, or manufacturer in the pharmaceutical, nutraceutical, cosmetic, or agricultural industry, our flavonoid products are designed to meet your specific needs. Experience the versatility and potential of flavonoids in your applications with our reliable and premium-quality products.

Product Category	CAS Number	Product Name	Purity	Molecular Formula
Flavonoids	20196-89-8	Kaempferol 7-O-rhamnoside	98%	C21H20O10
Flavonoids	18609-17-1	Quercetin-3-O-sophoroside	>98%	C27H30O17
Flavonoids	548-83-4	Galangin	>98%	C15H10O5
Flavonoids	654055-01-3	Morin hydrate	>98%	C15H10O7.xH2O
Flavonoids	482-36-0	Hyperin	98%	C21H20O12
Flavonoids	13463-28-0	Eriocitrin	>98%	C27H32O15
Flavonoids	552-58-9	Eriodictyol	>97%	C15H12O6
Flavonoids	29782-68-1	Silidianin	>98%	C25H22O10
Flavonoids	31524-62-6	Isobavachin	>98%	C20H20O4
Flavonoids	6754-58-1	Xanthohumol	>98%	C21H22O5

Please contact us for further information if you have a purchase requirement, including pricing, samples, and technical specifications. We look forward to providing our flavonoid products. In addition, ALL Chemistry provides a seamless one-stop process development service, ALL Chemistry can provide synthesis and fine chemical services if the existing products can't meet your needs, we have expertise in the synthesis of a broad array of customized molecules, and we offer lab scale custom synthesis, biosynthesis, bioconjugation and analytical services.

Product Advantage:

Provide quality-guaranteed products, all products are provided with a quality analysis report (COA), use advanced instruments such as MS(Mass Spectrometry), HPLC and NMR (Nuclear Magnetic Resonance) for quality inspection.

Professional and reliable packaging ensures the safety and stability of products from transportation, storage to use.

ALL Chemistry provides flavonoid products with a purity greater than 95%.

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